Detection of bacteria causing meningitis / encephalitis in humans using multiplex PCR and reverse hybridisation.

In vitro diagnostic kit for bacteria and fungi causing meningitis and encephalitis in humans using DNA Flow technology, providing reliable results for clinical laboratories and molecular microbiology.

ICONO 1 2

Multiplex
Detection

Simultaneous detection of 9 bacteria and 1 fungus associated with meningitis and encephalitis in CSF using multiplex PCR and DNA-Flow reverse hybridisation.

ICONOS 4 10

Clinically
Relevant Panel

Includes N. meningitidis, S. pneumoniae, S. agalactiae, L. monocytogenes, H. influenzae, M. tuberculosis complex, T. pallidum, C. burnetii, B. burgdorferi and C. neoformans.

ICONOS 4 11

High Sensitivity
and Specificity

Detection limits verified from 10 copies/reaction for various targets, with 100% analytical specificity and no cross-reactions between the included organisms.
ICONOS 3 14

Automation and
Objective Interpretation

Compatible with Vitro hybriSpot platforms, including HS12, HS24 and HS12 PCR AUTO, with automatic result analysis via hybriSoft.
ICONOS 3 15
DNA Flow

Bacterial CNS Flow Chip Kit

Detection of bacteria causing meningitis/encephalitis in humans using multiplex PCR and reverse hybridisation.
MAD-003935M-HS12-24 – 24 determinations
MAD-003935M-HS24-24 – 24 determinations

Kit Information
The Bacterial CNS Flow Chip kit is an in vitro diagnostic kit for bacteria and fungi causing meningitis and encephalitis in humans. Current diagnostic methods are very laborious and do not always show 100% specificity. The Bacterial CNS Flow Chip system allows for the simultaneous detection of nine bacterial species (Neisseria meningitidis, Streptococcus pneumoniae, Streptococcus agalactiae, Listeria monocytogenes, Haemophilus influenzae, Mycobacterium tuberculosis complex, Treponema pallidum, Coxiella burnetii, and Borrelia burgdorferi) and one fungus (Cryptococcus neoformans) through bacterial DNA amplification by multiplex PCR and subsequent reverse hybridisation on a membrane containing specific DNA probes for each species.

Rapid molecular diagnosis for bacterial meningitis/encephalitis

Bacterial meningitis continues to be a major public health problem, with over a million cases and more than 200,000 deaths annually worldwide. Rapid diagnosis is crucial for initiating appropriate treatment and improving patient prognosis.

Bacterial CNS Flow Chip enables the simultaneous detection of nine meningitis-causing bacteria using molecular hybridisation technology, providing a rapid, accurate, and highly sensitive diagnosis for clinical laboratories.

Benefits of DNA FLOW TECHNOLOGY

Cabeceras Multiplexacion
ICONOS 1 15

Advanced Multiplexing

Sensitive and specific simultaneous identification of genetic material from different pathogenic microorganisms and antibiotic resistance markers in a single assay.

Cabeceras Flexibilidad Diag
ICONOS 4 11

Diagnostic flexibility

Our reagents allow for the analysis of a wide spectrum of sample types, from blood to urine, swabs, liquid cytology, sputum, bronchial washes, among others. Applicable to different diagnostic areas.

Cabeceras Resultados Fiables
ICONOS 1 9

Fast and Accurate Results

Consolidated automated reverse hybridisation technology on a porous membrane microarray containing specific oligonucleotides for each marker.

Cabeceras Integracion 1
ICONOS 4 5

Safety and traceability

Complete sample control and bidirectional connectivity with LIS for secure and efficient diagnostic process management. Automated interpretation and full traceability via hybriSoft.

Technology for

Molecular Diagnosis

Specialised platforms for extraction, real-time PCR, reverse hybridisation, and traceability designed to improve laboratory diagnostic efficiency and reliability.

Vitrocycler

VitroCycler

Real-time PCR platform.

Hycrystpot

Hybrispot

PCR and reverse hybridisation system for molecular detection.

Mais

MAIS

MAIS Comprehensive molecular solution with full automation.

Victoria

MAIS Victoria V96

Fully automated instrument for the pre-analytical and analytical phases.

ARE YOU LOOKING FOR A COMPREHENSIVE SOLUTION FOR

YOUR DIAGNOSTIC LABORATORY?

Our specialised team helps you identify the most suitable technology, reagents, and instrumentation to optimise your diagnostic processes.

With Vitro’s Molecular Microbiology solutions, we improve laboratory automation, traceability, and efficiency, from sample to final result.

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